This is one of the few episodes where Cub is seen without Pop.
The flowers Lumpy holds are the same kind of flowers as in Giggles' Smoochie. Also, Giggles' sneeze in this episode is similar to her sneeze in her Smoochie.
Cuddles' hospital room is the same as Toothy's in Mime and Mime Again. It even has the same drawing of a rainbow on the wall in the background. The only differences is the lack of a window, the bed is on the right side of the wall, and the interior of the room is wider.
This is one of the four instances where Cuddles gets split in half, and his intestines are the only thing holding him together. The other three are I Get a Trick Out of You, See You Later, Elevator and Wingin' It.