- This is, so far, the only internet episode where Mime survived.
- This is one of the five Season 1 episodes to have a moral that has anything to do with the episode, instead of just a random piece of advice like "Read a book" or "Eat your veggies!". The others are Nuttin' but the Tooth, Wheelin' and Dealin', Water You Wading For, and Sweet Ride.
- This is the very first episode to entirely take place inside.
- This makes this one of the many episodes that have no trees.
- The YouTube thumbnail for the remastered version spoils Toothy's injury.
- There are no female characters in this episode.
- This is the first time a character has alcohol splashed on an open part of their body. The second time was in Easy Comb, Easy Go with Lumpy.
- If one looks closely when Toothy gets killed, a tin can be seen flung into the air, just like in Banjo Frenzy and Milkin' It.
- On Hulu, the characters are introduced with their season 2 starring pop-ups.
- Toothy's body parts that were shredded by the fan:
- His bandaging
- Pieces of his spinal cord
- 2 pieces of his torso (one has a piece of his spine and the other one has another piece of his spine as well as his ribs)
- His arms
- The episode's title is a pun of the idiom "time and time again", which means to happen over and over again.
- The moral for this episode is used to say that it is often better to remain silent than to speak.
- In the 2nd DVD commentary, one of the people mentioned how the picture of a rainbow seen on the wall was snuck in by one of the animators, who was fired.
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